STUDY OF ANTI-HYPERTENSIVE DRUG UTILIZATION PATTERN IN CHRONIC KIDNEY DISEASE PATIENTS

  • Amish Uprety Nargund College of pharmacy Bangalore, Karnataka, India.

Abstract

Introduction: Hypertension is a chronic illness associated with high morbidity & mortality, with a rising number of patients with hypertension and chronic kidney disease, achieving blood pressure of less than 140/90 mm of Hg is challenging. Hence, there is a need for appropriate, safe, effective and economical study to find out the patterns of drug therapy.
Objectives: To evaluate utilization patterns of antihypertensive agents in chronic kidney disease patients.
Methodology: A prospective observational study was conducted for a period of 6 months in Jayanagar General Hospital, Bengaluru. We included 70 hypertensive CKD patients. Detailed patient information data were noted, and data entered in a preformed proforma in Microsoft Excel sheet for compilation and subjected to statistical analysis.
Results: Total 70 case records of patients having chronic kidney disease were analysed. Mean age was 52.08 ± 15.14. CKD was more prevalent in males 38 (54.2%) and 32 (46.8%) females with male to female ratio of 2.3:2. Most of the patients (52.80%) belonged tote age group of 41-60 years. Among the anti-hypertensive agents, most frequently used was calcium channel blockers (91.4%), followed by diuretics (54.2%), Beta blockers (31.4%), alpha blockers, ACE inhibitors and ARB.
Conclusion: Dual and triple therapy were prescribed which was according to ESH
guidelines. This study highlights some therapeutic rationality in this health centre. However,targeted education of the prescription-givers and dissemination of treatment guideline could facilitate rational use of drugs and adherence to treatment guidelines.

Published
Aug 19, 2019
How to Cite
UPRETY, Amish. STUDY OF ANTI-HYPERTENSIVE DRUG UTILIZATION PATTERN IN CHRONIC KIDNEY DISEASE PATIENTS. International Journal of Drug Research and Technology, [S.l.], v. 9, n. 3, p. 252-270, aug. 2019. ISSN 2277-1506. Available at: <http://ijdrt.com/index.php/drug-research-and-technology/article/view/207>. Date accessed: 14 dec. 2019.
Section
Research Article
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