A REVIEW ON MEDICINAL PLANTS USED AS A SOURCE OF ANTICANCER AGENTS
In this review we describe and discuss several approaches to selecting higher plants as candidates for drug development with the greatest possibility of success. We emphasize the role of information derived from various systems of traditional medicine (ethnomedicine) and its utility for drug discovery purposes. Cancer is a major public health burden in both developed and developing countries. An attempt has been made to review some medicinal plants used for the prevention and treatment of cancer. Medicinal herbs have been on the forefront whenever we talk about anticancer remedies, Herbal medicines have a vital role in the prevention and treatment of cancer. With advanced knowledge of molecular science and refinement in isolation and structure elucidation techniques, various anticancer herbs has been identified, which execute their therapeutic effect by inhibiting cancer-activating enzymes and hormones. Several anticancer agents including taxol, vinblastine, vincristine, the camptothecin derivatives, topotecan and irinotecan, and etoposide derived from epipodophyllotoxin are in clinical use all over the world. A number of promising agents such as flavopiridol, roscovitine, combretastatin A-4, betulinic acid and silvestrol are in clinical or preclinical development.
Anticancer, Medicinal plants, Herbal medicine, Taxol, Cancer treatment.