EVALUATION OF WOUND HEALING ACTIVITY OF ETHANOLIC EXTRACT OF OCIMUM BASILICUM AND AEGLE MARMELOS LEAVES IN MALE ALBINO RATS

  • Renu Solanki Others, Lachoo Memorial College Of Science And Technology, INDIA
  • Vipin Mathur Others, Lachoo Memorial College Of Science And Technology, INDIA
  • Shiv Kumar Purohit Others, College Of Veterinary And Animal Science, Rajasthan Agricultural University, INDIA
  • Manoj Mathur Others, College Of Veterinary And Animal Science, Rajasthan Agricultural University, INDIA

Abstract

Wounds are major cause of physical disabilities. Wound healing consists of orderly progression of series of events that establish the integrity of the damaged tissues. Aegle marmelos (Bael) is used for medicinal purposes, including treatment of dyspepsia, inflammation, asthma, hypoglycemia, cancer, hepatitis, diabetes, sinusitis, tuberculosis, diarrhea, dysentery, as astringent, digestive, stomachic etc. Recent pharmacological studies have established various pharmacological properties of Ocimum basilicum (Ban-tulsi) like anabolic, hypoglycemic, smooth muscle relaxant, cardiac depressant, antifertility, adaptogenic, antifertility, antidiabetic, antimicrobial, antiallergic and immunomodulator properties. The present study was undertaken on ethanolic extract of leaves of Aegle marmelos and Ocimum basilicum on wound healing activity through topical route on excision wound model. The activity was compared with standard drug povidone iodine ointment (5% w/w) respectively. The leaves of Aegle marmelos ethanolic extract was found to have better wound healing effect than ethanolic extract of leaves of Ocimum basilicum on excision wound model. The leaves of Aegle marmelos ethanolic extract also showed faster rate of healing when compared with standard topical application.


Keywords

Aegle marmelos, Ocimum basilicum, Wound healing activity, Excision wound model.

Published
Feb 28, 2017
How to Cite
SOLANKI, Renu et al. EVALUATION OF WOUND HEALING ACTIVITY OF ETHANOLIC EXTRACT OF OCIMUM BASILICUM AND AEGLE MARMELOS LEAVES IN MALE ALBINO RATS. International Journal of Drug Research and Technology, [S.l.], v. 2, n. 2, p. 4, feb. 2017. ISSN 2277-1506. Available at: <http://ijdrt.com/index.php/drug-research-and-technology/article/view/evaluation-of-wound-healing-activity-of-ethanolic-extract-of-ocimum-basilicum-and-aegle-marmelos-leaves-in-male-albino-rats>. Date accessed: 16 nov. 2019.
Section
Research Article
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