RECENT ADVANCE IN ANTI INFLAMMATORY ACTIVITY OF BENZOTHIAZOLE DERIVATIVES
Different heterocyclic compounds are made to synthesize by large number of efforts and their derivatives were found to possess antitumor, antidiabetic, antimicrobial, anticonvulsant and anthelmintic activities.
The small and simple benzothiazole nucleus and its derivatives possess various diverse biological properties. These activities are also possessed by its substituted derivatives as well. Literature revealed that benzothiazole derivatives may serve as an important model on as potent anti-inflammatory agent. When one biological active molecule is linked to another, resultant molecule generally has increased potency. Most of the derivatives showed enhanced anti-inflammatory activity as compared to the standard drug. So, benzothiazole derivatives can serve as future therapeutic leads for the discovery of anti-inflammatory drugs.
Heterocyclic compounds, Benzothiazole, Biological properties, Anti-inflammatory agents, Anti-inflammatory drugs.