RECENT ADVANCE IN ANTI-CANCER ACTIVITY OF INDOLE DERIVATIVES
The recent identification of an indole analog as a potential new anticancer lead. Indole nucleus is continuously drawing interest for development of newer drug moiety due to its wide range of activities like anticancer, antibacterial, antifungal, anti-malarial, anticonvulsant and anti-inflammatory. The research is going on in nucleus. In recent years, a wide range of research has been done in the field of anti-cancer drug development. Since indole nucleus has shown quite good response as an anticancer agent, hence this nucleus has become an interest in the field of research. Indole is present in Vinca alkaloid which can be used as an anti-cancer agent. So keeping in mind this point indole has been used for better anti-cancer activity of target compound. The pyridine nucleus is an essential part of many anti-cancer derivatives. So, it was thought of interest to synthesize compounds having Indole moiety with pyridine which might possess potent anti-cancer activity.
Indole, Pyridine, Anticancer, Antibacterial, Antifungal, Anti-malarial, Anticonvulsant, Anti-inflammatory.