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Abstract
The majority of drugs work by interacting with chiral counterparts, such as proteins, and unfortunately, we are well aware of how chirality can affect how a treatment works. Preparing chiral, non-racemic drugs in a safe, cost-effective, and sustainable manner is becoming increasingly important as the number of these drugs on the market grows. Although asymmetric organ catalysis has a long history, it did not begin its renaissance until the early. The award of the Chemistry Nobel Prize demonstrates that this field has progressed to an extraordinary level since that time. The use of organ catalysis in the synthesis of enation-enriched molecules, which October be of interest to the pharmaceutical industry and the medicinal chemistry community, is the focus of this review.
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