International Journal of Drug Research and Technology

A Method for Preclinical Research that Isolates and Analyses Drugs from Cancer Cells

Abstract

Sand Born*

Cancer remains a global health challenge, necessitating the continuous development of novel therapeutic strategies. In recent years, there has been growing interest in harnessing the potential of cancer cells themselves to isolate and analyze naturally occurring anticancer drugs. This preclinical research study presents a method that combines advanced cell culture techniques, high-throughput screening, and molecular analysis to identify and characterize potential drug candidates derived from cancer cells for targeted cancer therapy. The research protocol involves the establishment of primary cancer cell cultures from various malignancies, representing a diverse range of tumour types. These cultures are systematically subjected to extensive screening using a library of compounds, including plant extracts, natural products, and synthetic small molecules. The screening process employs state-of-the-art techniques to assess the cytotoxic effects of each compound on cancer cells, while sparing healthy cells, thereby maximizing therapeutic selectivity.