International Journal of Drug Research and Technology

DRUG RESEARCH TECHNOLOGIES TO UNDERSTAND DRUG TOXICITY MECHANISMS

Abstract

Cha Ren*

Drug development and medical care both depend heavily on rug safety. Drug safety is primarily concerned with preventing adverse medication events, which are harms brought on by any drug-related action. Annually, adverse medication events in the USA result in about 3.5 million outpatient doctor visits and 2 million inpatient hospital admissions. Some adverse drug events, such as dosage errors, overdoses, and allergic responses, can be avoided, whilst others are expressly referred to be adverse drug reactions or drug side effects because they are brought on by underlying drug-induced mechanisms. It is crucial to avoid these side effects in healthcare in order to improve both clinical and financial outcomes.

Along with structure- and ligand-based approaches, there are other in silico techniques for virtual compound screening that enable better profile analysis, quicker non-target compound elimination, and more cost-effective selection of therapeutic molecules. The physical, chemical, and toxicological properties are taken into account by drug design algorithms like coulomb matrices and molecular fingerprint identification to choose a lead compound.

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